When diagnosed with breast cancer, there are many questions that arise. It is important to learn and understand available treatment options in order to take control of your health.
Breast Cancer Program at Kathmandu Cancer Centre offers the highest-quality care for screening, diagnosis and treatment of breast cancer. This website helps you to understand your options for Breast Cancer Treatment.
Breast Cancer Information
When to see a doctor
You should make an appointment with your doctor as soon as you find a lump in your breast. Each year, more than 15,000 Nepali women are diagnosed with Breast Cancer. In Nepal, because of lack of awareness , many patients present at an advanced stage – unlike in developed countries.
- Skin changes, such as swelling, redness, or other visible differences in one or both breasts
- An increase in size or change in shape of the breast(s)
- Changes in the appearance of one or both nipples
- Nipple discharge other than breast milk
- General pain in/on any part of the breast
- Lumps or nodes felt on or inside of the breast
Even if you don’t have any symptoms, it is better to do screening test regularly. See the guideline for screening here.
For screening package in KCC hospital, please click here.
Research shows that there are several risk factors that may increase your chances of developing breast cancer. These include:
Age: Being 55 or older increases your risk for breast cancer.
Sex. Women are much more likely to develop breast cancer than men.
Family history and genetics. If you have parents, siblings, children or other close relatives who’ve been diagnosed with breast cancer, you’re more likely to develop the disease at some point in your life. About 5% to 10% of breast cancers are due to single abnormal genes that are passed down from parents to children, and that can be discovered by genetic testing.
Smoking. Tobacco use has been linked to many different types of cancer, including breast cancer.
Alcohol use. Research indicates that drinking alcohol can increase your risk for certain types of breast cancer.
Obesity. Being fat can increase your risk of breast cancer and breast cancer recurrence.
The stages of breast cancer are used to describe the extent of your cancer at the time of diagnosis. Your doctor will base the stage of your cancer on a physical exam and other diagnostic tests. This is known as clinical stage. The final, or pathologic, stage is determined after surgery when the size of the cancer is measured under a microscope and it is definitely known if there is cancer in the lymph nodes.
Stage I– Small tumor localized to breast only
Stage II– Tumor in breast and axillary nodes on the same side
Stage III– Locally advanced Breast cancer ( LABC)- Large tutor in breast which may involve skin or chest wall or multiple fixed nodes in axilla, neck or inside the chest.
Stage IV– The cancer has spread to other parts of body like liver, lung, bone, brain etc.
Breast cancer subtypes
There are 3 main subtypes of breast cancer that are determined by doing specific tests on biopsy or surgical sample. Treatment and outcome depend on this subtype.
Hormone receptor positive. Breast cancers expressing estrogen receptors (ER) and/or progesterone receptors (PR) are called “hormone receptor positive.” These receptors are proteins found in cells. Tumors that have estrogen receptors are called “ER positive.” Tumors that have progesterone receptors are called “PR positive.” This type of cancer may depend on the hormones estrogen and/or progesterone to grow. Hormone receptor-positive cancers can occur at any age, but are more common in older woman who already had menopause . Cancers without these receptors are called “hormone receptor negative.”
HER2 positive. About 20% of breast cancers depend on the gene called human epidermal growth factor receptor 2 (HER2) to grow. These cancers are called “HER2 positive” and have many copies of the HER2 gene or high levels of the HER2 protein. These proteins are also called “receptors.” The HER2 gene makes the HER2 protein, which is found on the cancer cells and is important for tumor cell growth. HER2-positive breast cancers grow more quickly. They can also be either hormone receptor positive or hormone receptor negative. These cancer are treated with Anti-Her2 targeted drugs like Herceptin.
Triple negative. If a tumor does not express ER, PR, and HER2, the tumor is called “triple negative.” Triple-negative breast cancer makes up about 15% of invasive breast cancers. Triple-negative breast cancer seems to be more common among younger women,. Triple-negative breast cancer is also more common in women with a mutation in the BRCA1 gene. These tumor are very fast growing but usually shrink after chemotherapy. So they are usually treated with chemotherapy before surgery.
Treatment of Breast Cancer
We offer a complete range of options to treat breast cancer and our breast care specialists will help to determine the best treatment plan based on type of breast cancer, size and location of the tumor, disease stage, lab test results, and the individual’s overall health.
Modern breast cancer treatment usually involves a combination of following approaches.
- Surgery to remove only breast tumor ( breast saving surgery)
- Surgery to remove whole breast (Mastectomy)
- Onco-Plastic reconstructive surgery
- HER-2 Targeted therapy.
- Hormone therapy
- Neoadjuvant chemotherapy (chemotherapy before surgery)
- Breast Brachytherapy
- Breast Cancer Screening.
Why choose Kathmandu Cancer Center for Breast cancer treatment in Nepal ?
Breast Cancer management in this current era is a teamwork and involves the combined team effort of surgical, medical and radiation oncologists. We approach all cases in a holistic way. The cases are discussed in tumor board to decide the best treatment protocol for them and then they are explained the treatment plan. This individualized treatment plan gives every patient their best chance of cure.
We delivers a broad range of breast cancer treatments, and breast surgery. Our experts are fellowship-trained doctors. We help you look and feel your best after cancer treatment with specialized services such as onco-plastic reconstructive surgery . Preserving quality of life and going back to work and leaving healthy life are important treatment goals for these patients.
Area of expertise of our medical team:
- Breast saving surgery, Onco-plastic surgery
- Breast Brachytherapy
- Heart-saving radiotherapy in left sided breast cancers (DIBH)
- Targeted therapy and chemotherapy according to international protocols.
- Neo-adjuvant chemotherapy for Triple negative breast cancer
- Treatment of familial and BRCA positive cancers.
Breast Cancer Team
Dr Banira Karki – Breast Onco-plastic surgery
Dr Deep Lamichhane – Surgical Oncology
Dr Subhas Pandit – Clinical Oncology
Dr Simit Sapkota – Clinical Oncology
Dr Sundar Suwal – Intervention Radiology
Dr Sanat Chalise – Pathology
Contact us now for appointment or consultation.